Pang et al. (2010) used differential in-gel electrophoresis-based proteomics analysis and found that PPA2 was overexpressed in patients with lymph node metastatic prostate cancer, suggesting the potential diagnostic value of PPA2. Uzozie et al. (2017) also found that PPA2 expression was upregulated in colorectal adenomas using a targeted proteomics approach. Here, PPA2 is linked to colorectal adenoma.