Furthermore, several genes, including TNF, mucin 22 (MUC22), testis-expressed basic protein 1 (TSBP1), transporter 2, ATP binding cassette subfamily B member (TAP2), and inositol 1,4,5-trisphosphate receptor type 3 (ITPR3) located near the HLA-J gene in chromosome 6 were found to be related to hyperthyroidism risk in the present study. Here, TNF is linked to hyperthyroidism.