SNCA and synucleinopathy: However, they observed that ASRS fails to inhibit α-synucleinopathies but produces some potential neurotoxicity to CNS under physiological conditions, indicated by no significant difference in the expression of lncRNA/mRNA that may cause potential neurotoxicity analogous to α-synuclein that exists between ASRS-treated and -untreated α-synuclein mice in physiological conditions [113].