Previous studies reported that calreticulin and phosphatidylserine could induce phagocytosis by binding to the low-density lipoprotein receptor-associated protein (LRP) on phagocytes, as blocking the CD47-SIRPα antiphagocytic signal induced an effective prophagocytic signal to trigger tumor phagocytosis [13, 14]. Here, CALR is linked to neoplasm.