The presence of inflammation in T2DM has been demonstrated years ago through cohort studies that revealed higher incidence of the disease in patients with higher level of acute-phase proteins such as C-reactive protein (CRP) and proinflammatory cytokines such as interleukin-6 (IL-6) in comparison to the subjects with normal values of these markers [111]. The gene discussed is CRP; the disease is type 2 diabetes mellitus.