After administration of Cur, the percentage of CD11b+F4/80+iNOS+ (Figure 5(e)) macrophages in colitis mice was significantly downregulated, and those of M2 macrophage CD11b+F4/80+CD206+ (Figure 5(f)) and CD11b+F4/80+CD163+ (Figure 5(g)) macrophages were significantly upregulated. The gene discussed is MRC1; the disease is colitis.