Importantly, the concentrations of CCL-2 (Figure 2(a)), IL-1β (Figure 2(b)), and IL-6 (Figure 2(c)) were significantly downregulated after DSS-induced colitis mice were treated with curcumin; IL-33 (Figure 2(d)) and IL-10 (Figure 2(e)) were significantly upregulated. This evidence concerns the gene IL1B and colitis.