The expression of each TLR was quantified as the MFI and the medians, and ranges of each group were plotted (Figure 6), which showed that the peripheral blood NK [CD16+] cells of patients with ALL exhibited lower TLR1 (297.8 versus 748.3; P=0.0042) and TLR9 expression (100.2 versus 190.7; P=0.0098) compared with the control group. The gene discussed is TLR9; the disease is acute lymphoblastic leukemia.