For breast cancer, at sites S256 (P-value = 3.55 E-07), S195 (P-value = 1.44 E-06), and S196 (P-value = 1.50 E-05), CBX8 protein phosphorylation levels were significantly higher than those in adjacent normal tissues, but this association was not observed in S110 (P-value = 6.31 E-02) (Figure 4A). The gene discussed is CBX8; the disease is breast carcinoma.