KIF23 and neoplasm: Deng et al. (2017) revealed that expression of the tumor suppressor miR-199a-3p was significantly down-regulated in OC cells, and its promoter was hypermethylated in OC cells. Overexpression of miR-199a-3p can inhibit the migration, invasion, and tumorigenic capabilities of OC cells as well as enhance cisplatin resistance by inhibiting targeted DDR1 expression. Similarly, expression of the miR-424/503 cluster is inhibited by DNA hypermethylation in the promoter regions, which promotes the expression of KIF23, thereby improving the oncogenic performance of OC cells (Li et al., 2019).