Deng et al. (2017) revealed that expression of the tumor suppressor miR-199a-3p was significantly down-regulated in OC cells, and its promoter was hypermethylated in OC cells. Overexpression of miR-199a-3p can inhibit the migration, invasion, and tumorigenic capabilities of OC cells as well as enhance cisplatin resistance by inhibiting targeted DDR1 expression. Similarly, expression of the miR-424/503 cluster is inhibited by DNA hypermethylation in the promoter regions, which promotes the expression of KIF23, thereby improving the oncogenic performance of OC cells (Li et al., 2019). Here, DDR1 is linked to neoplasm.