Results revealed that high levels of MAP3K8 expression were associated with poorer prognosis of OS in ccRCC (GEPIA: Log-rank P = 0.60E-2, HR = 1.5; DriverDBv3: Log-rank P = 1.68E-7, HR = 2.21; UALCAN: P = 0.20E-2) (Figures 5A–C). Here, MAP3K8 is linked to nonpapillary renal cell carcinoma.