Few significant interactions were observed between OS and clinicopathological features, indicating that tumor grade (P < 1.0E-4), patient race (P = 1.9E-2), and patient gender (P = 1.3E-2) may influence the prognosis of ccRCC patients with high-level MAP3K8 expression (Figures 5D–F). This evidence concerns the gene MAP3K8 and nonpapillary renal cell carcinoma.