LINC00894 can inhibit the TGF-β2/ZEB1 signaling pathway by acting as the sponge of EMT-regulating miR-200, or can be upregulated by ERα activation and positively regulate the expression of miR-200a-3p and miR-200b-3p, which results in induction of the TGF-β2/ZEB1 signaling pathway to reduce the occurrence of drug resistance in breast cancers (Zhang et al., 2018; Farhan et al., 2019; Huang et al., 2020). This evidence concerns the gene TGFB2 and breast carcinoma.