In the present study of 93 anti-Dsc autoantibodies cases, the most common phenotype was PH in patients with either IgG or IgG/IgA anti-Dsc and anti-Dsc/Dsg autoantibodies; SPD in patients with IgA anti-Dsc autoantibodies; and PNP-like in those with antibodies against multiple antigens. The gene discussed is DSC3; the disease is Platelet storage pool disease.