Moreover, the percentage of HLA-DR+CD38hi CD8+ T cells was found to have positive correlations with aspartate transaminase (AST) and total bilirubin (TB) in COVID-19 patients (R=0.397, P<0.0001; R=0.398, P<0.0001), and a strong negative correlation with albumin (R=−0.481, P<0.0001). Here, CD8A is linked to COVID-19.