Sepsis induces a systemic dysregulated inflammatory response that is characterized by the excessive production of inflammatory mediators [e.g., interleukin-1β (IL-1β), interferon-γ (IFN-γ), tumor necrosis factor-α (TNF-α), granulocyte-Colony stimulating factor (G-CSF), interleukin-10 (IL-10) and transforming growth factor-β (TGF-β)] and the inflammatory inducer [lipopolysaccharide (LPS)] (12). The gene discussed is IL1B; the disease is Sepsis.