CD8A and neoplasm: Besides, ssGSEA analysis of 22 gene sets involved in the activation of CD8 alpha-beta T cell and adaptive immune response found that these pathways scored significantly higher in the IFNGrGS score-high group (logFC > 0 and adjust p-value < 0.001) (Figure 3B), with the logFC values of immunosuppressive biological processes were constantly higher than corresponding immuno-stimulatory processes (Table 1), possibly revealing an activated but suppressed anti-tumor immune response.