In the correlation analysis of GDF15 and laboratory indicators, we observed that GDF15 was correlated with biomarkers of liver, kidney, and heart damage, which was not difficult to explain, because previous studies found that GDF15 had changes in many organ-related diseases (40–42), and the course of sepsis involved multiple organ injuries, so this result was in line with expectations, which is also the same as the previous findings (15, 43). The gene discussed is GDF15; the disease is Sepsis.