ANXA1 and chronic obstructive pulmonary disease: Annexin A1 and its derivative peptides have been shown to have therapeutic effect in various disease states, including sepsis (Gavins et al., 2012; Zhang et al., 2018), lung inflammation (da Cunha et al., 2012) and chronic obstructive pulmonary disease (COPD) (Possebon et al., 2018), myocardial infarction (D’ Amico et al., 2000; La et al., 2001; Qin et al., 2015), and intestinal wound repair (Babbin et al., 2008).