NQO1 and chronic obstructive pulmonary disease: In previous study, we reported that lncRNA Fantom3_F830212L20 and Nqo1 were co-expressed lncRNA and protein-coding gene, and both of two were significantly up-regulated in lung tissues of chronic CS-induced COPD mouse model, 16HBE cells and A549 cells exposed to CSE treatment when compared to their controls (Zhang et al., 2018b).