SOCS3 and type 2 diabetes mellitus: Moreover, compared with those who exposed to low levels of serum progesterone and high level of Chr17:76356190 or Chr17:76356199 (SOCS3) methylation, individuals who exposed to high levels of progesterone and low level of Chr17:76356190 or Chr17:76356199 (SOCS3) methylation had the highest risk of prevalent T2DM.