INS and type 2 diabetes mellitus: Compared with control group, individuals with T2DM were more likely to have higher body mass index (BMI), pulse pressure (PP), triglyceride (TG), fasting plasma glucose (FPG), insulin (INS), glycosylated hemoglobin A1c (HbA1c), progesterone levels and lower levels of Chr17:76356190 and Chr17:76356199 methylation, as well as had family history of T2DM (all P < 0.05) in both men and postmenopausal women.