TPD52 and osteosarcoma: In addition, anti-TPD52 antiserum reduced the volume (ANOVA, F(5, 24) = 60.14, P < 0.0001; Fig. 4b–d) and weight (ANOVA, F(5, 24) = 91.57, P < 0.0001; Fig. 4e) of osteosarcoma in a dose-dependent manner, indicating that antiserum inhibits the growth of osteosarcoma.