PTEN and neoplasm: In line with our study, T2-weighted MRI has been used to monitor tumor volume reduction after monotherapy with rapamycin in a genetically engineered mouse model of EC (Lkb1-deficient) [34] and after combined treatment with Olaparib and a PI3K-inhibitor (BKM120) in PTEN-deficient endometrioid EC model [35].