LGALS3BP was demonstrated to interact with various extracellular matrix proteins including laminin-1, laminin-5, laminin-10, fibronectin, collagen IV, as well as galectin-3; and although to a lesser extent with collagen I and galectin-1; while, in contrast to previous findings, it was unable to mediate adhesion of seven colon cancer cell lines and a sampling of normal cell lines, suggesting that LGALS3BP produced by HT- 29 cells is a poor cell-adhesive substratum [71]. This evidence concerns the gene LGALS3 and colonic neoplasm.