Results from this work revealed either increased Lamp-1, Lamp-2, and LGALS3BP gene transcription or increased mRNA stability in pancreatic carcinomas in vivo, and at protein level, primary carcinoma samples and their corresponding lymph node metastasis overexpressed all three ligands concomitantly in the pancreatic carcinoma cells. The gene discussed is LAMP2; the disease is exocrine pancreatic carcinoma.