Results from this work revealed either increased Lamp-1, Lamp-2, and LGALS3BP gene transcription or increased mRNA stability in pancreatic carcinomas in vivo, and at protein level, primary carcinoma samples and their corresponding lymph node metastasis overexpressed all three ligands concomitantly in the pancreatic carcinoma cells. Here, LAMP1 is linked to exocrine pancreatic carcinoma.