The expression levels of EMMPRIN mRNA and protein in MCF-7 cells were significantly decreased after infection with the EMMPRIN-shRNA lentivirus, which was proven through EMMPRIN shRNA in breast cancer MCF-7 cells using the lentivirus-induced RNAi technique to investigate the changes in breast cancer proliferation potential under conditions of EMMPRIN gene deletion. Here, BSG is linked to breast carcinoma.