MAPK8 and cardiomyopathy: inhibited DOX-induced apoptosis of cardiac muscle cells via suppressing JNK signaling pathway [13]; Samar S Elblehi et al. demonstrated that date palm pollen extract averts DOX-induced cardiomyopathy fibrosis by suppressing apoptosis-targeting Bax/Bcl-2 and caspase-3 signaling pathways [14].