On the other hand, a recent study using bioinformatics have shown that AP1S1 expression is related to glioblastoma multiforme (GBM) pathogenesis [50] and is hypo-methylated and upregulated in acute myeloid leukemia (AML) [51] indicating that its upregulation might have pathological effects in cancer. Here, AP1S1 is linked to glioblastoma.