Among these miRNAs, miR-106b-5p, which has predicted binding sites in LOC107985656 and the 3ʹUTR of LATS1 (Figure 5(b)), was selected for further investigation because of its possible oncogenic role in HCC via regulating several target genes, such RUNX3 [22], PTEN [23] and FOG2 [24]. The gene discussed is PTEN; the disease is hepatocellular carcinoma.