Next, we analyzed the effects of the drugs on the ratio of activated caspase-3/7 positive cells (as a marker of apoptosis) in the K562 (Fig. 3A) and KCL-22 (Supplementary Fig. 2) CML lines with fluorescence live cell microscopy. The gene discussed is CASP3; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.