Ge et al. (50) found that steroids (specifically dexamethasone) and cyclosporine can inhibit TLR4 expression, thus negatively regulating NF-κB signaling in an OLP model; in addition, cyclosporine could induce apoptosis and thus inhibit cell proliferation of human keratinocytes. This evidence concerns the gene NFKB1 and oral lichen planus.