IL6 and arthritic joint disease: (2) In cases of inflammatory pain, interleukin-6 (IL-6) and tumour necrosis factor-α (TNF-α) levels were found to be decreased by BVA (Species: Apis dorsata(A. dorsata), AR: oral route, dose: 2.0 mg/kg) in a collagen type-II induced arthritis pain model [22].