Moreover, TNF-α was decreased significantly after treatment with LPS and feline AD-MSC-derived exosomes simultaneously (186.75 ± 26.45 pg/mL) compared with treatment with LPS alone (336.80 ± 119.55 pg/mL) or LPS together with feline fibroblast-derived exosomes (373.04 ± 59.25 pg/mL). This evidence concerns the gene TNF and Alzheimer disease.