GNAT3 and constipation disorder: The subsequent ANOVA analysis showed that the fecal concentration of 10 of the 16 measurable bile acids, CA (p = 0.0002), CDCA (p = 0.001), GHDCA (p = 0.015), GDCA (p = 0.030), HCA (p = 0.025), GCA (p = 0.006), taurine (p = 0.018), TLCA (p = 0.007), TCDCA (p = 0.021), and TDCA (p = 0.018) were significantly different between healthy control, constipation (FC + IBS-C), and diarrhea (FD + IBS-D) groups (Figure 4).