CPT1A and nonpapillary renal cell carcinoma: Furthermore, integrated lipidomic and transcriptomic analyses showed that alterations in cellular lipid composition in ccRCC were accompanied by multiple consistent changes in gene expression, including increased CD36 (fatty acid uptake), stearoyl-CoA desaturase and fatty acid elongases 2 and 5 (fatty acid synthesis), reduced carnitine palmitoyltransferase 1A (CPT1A, rate-limiting enzyme for the transport of fatty acids into mitochondria for beta-oxidation), as well as perilipin 2 (triglyceride storage in lipid droplets) [64].