In particular, this miRNA promotes proliferation and invasiveness in gonadotroph and corticotroph adenoma cells through regulating phosphatase and tensin homologue (PTEN)/AKT, mitogen-activated protein kinase (MAPK), and activator of transcription 3 (STAT3) signaling pathways, while it has an opposite effect on somatotroph pituitary adenoma cells. This evidence concerns the gene AKT1 and pituitary gland adenoma.