CAMKK2 and obesity due to melanocortin 4 receptor deficiency: This has been further reflected in the involvement of CAMKK2 in several metabolic diseases characterized by the manifestation of dysregulated mitochondrial function as part of their pathogenic process, including, for example, cancer [84, 90–92], obesity [83], diabetes [54], neurodegeneration [16, 17], and NAFLD [76].