Molecular pathological analysis using IHC demonstrated that the positive rates of cyclin B, cyclin E, and Ki-67 in the internal tissue of intravenous leiomyomatosis were slightly higher than those of normal uterine leiomyoma (i.e., external tissue of intravenous leiomyomatosis) (Figure 1). This evidence concerns the gene MKI67 and Uterine leiomyoma.