Studies of matriptase proposed that the pro-metastatic effect of the cancer-associated glycosyltransferase N-acetylglucosaminyltransferase V (GnT-V) in gastric cancer cells was mediated by modification and stabilization of active matriptase upon addition of β1 to 6 GlcNAc branching (75). The gene discussed is ST14; the disease is gastric cancer.