Our study was designed as a pilot study to generate hypotheses for further studies, and has inherent strengths and weaknesses: some observations indicated a potential mechanism for HSA on mucosal healing beyond the mere hemostatic effect, though none of these reached the level of significance in our exploratory statistical analysis: In the stomach, at day 2 after induction of the ulcers, the mean relative size of the ulcers in the HSA treated group of pigs was smaller than in the group without treatment. This evidence concerns the gene ALB and ulcer disease.