SEMA7A and breast cancer: To determine a role for SEMA7A in breast cancer, we examined SEMA7A expression in breast cancers in The Cancer Genome Atlas (TCGA) to show that SEMA7A is significantly upregulated in primary tumors (Fig. 6a), is increased in all stages (Fig. 6b), is upregulated in breast cancers in women of all ages (Fig. 6c) and is expressed in every major subtype of breast cancer with highest expression occurring in the triple-negative class when compared to normal breast tissues (Fig. 6d and Supplemental Fig. 10).