The incidences of AKI within 48 h after ICU admission (50.5% vs. 37.9% and 17.5%; p < 0.001) and dialysis dependency (6.8% vs. 4.9% and 0%; p = 0.034) were greater among patients in the high Gal-1 tertile than among those in the median and low tertiles. The gene discussed is LGALS1; the disease is acute kidney injury.