Even if we presented Gal-1 value as a continuous variable (S2 Table), grouped patients according to the criterion value of ROC curve (S3 Table), or grouped by the serum Gal-1 values of reported viral (S4 Table) or bacterial infection (S5 Table), critically ill patients with higher Gal-1 levels were still significantly associated with greater 90-days mortality. The gene discussed is LGALS1; the disease is bacterial infectious disease.