CDH1 and colorectal carcinoma: In detail, the antiproliferative effects of Vitamin D in CRC includes the VDR binding to β‐catenin (preventing the activation of TCF7L2 complexes in the nucleus), the upregulation of the protein CDH1 (E‐cadherin), a transmembrane protein whose intracellular tail attracts β‐catenin, and the inhibition of the proto‐oncogene MYC (upregulated by the WNT/β‐catenin pathway).