VWF and atrial fibrillation: Combining vWF:Ag and ADAMTS13 levels, participants with vWF:Ag levels ≥ 1.61 IU/mL and ADAMTS13 activity ≤ 80.31% had a significantly higher risk of new-onset AF than participants with vWF:Ag < 1.61 IU/mL and ADAMTS13 activity > 80.31% [HR (95% CI): 1.47 (1.09–1.98)], albeit nonsignificant after adjustments (Table 2).