VEGFA and neoplasm: The interaction between c-MET and membrane receptors affects the role of signal molecules such as HGF/c-Met signal pathway and vascular endothelial growth factor and its receptor, and further affects the process of tumor invasion, metastasis, and neovascularization, which leads to the emergence of tumor drug resistance, and is an important reason for the failure of drug therapy.[22] Therefore, the key to inhibiting tumor growth is to find an inhibitor of c-MET to limit its activity, so as to resist tumor growth.