Labussiere et al. have found that TERTp mutations may be associated with poorer outcome in high-grade gliomas (31), however, Pekmezci et al. have reported that TERT-mutants had significantly worse survival only in IDH-WT astrocytoma, which includes grades II and III (10). The gene discussed is IDH1; the disease is astrocytoma (excluding glioblastoma).