The discovery of TERT p mutations in numerous gliomas has opened the door for a better molecular classification of gliomas in 2013 (20,21). TERT promoter mutations occur in 70-80% of glioblastomas, 95% of oligodendrogliomas, and 10-25% of astrocytomas (5,7,11). The gene discussed is TERT; the disease is glioblastoma.