This resulted in an indirect effect of sP-selectin levels on the MoCA score through BDNF in CAD participants (b = 0.11, CI = 0.01–0.22) that was significantly weaker than in non-CAD participants (b = 0.18, CI = 0.02–0.35), with a difference of −0.07 (−0.14 to −0.01) (Figure 3B). The gene discussed is BDNF; the disease is coronary artery disorder.