METTL3 and lobular neoplasia: Li et al. (2017) demonstrated that the m6A “writer” protein METTL3 regulates the homeostasis and differentiation of mouse T cells. However, no study has attempted to explore how m6A modification plays a role in LN, and the association between m6A modification and immune characteristics remains to be elucidated. The aim of this study was to clarify the role of m6A RNA methylation modification in LN and explore how m6A affects the immune status of LN.