PDK4 and hepatocellular carcinoma: Interestingly, as shown Figures 6(g)–6(j), HCC patients in the ERH-lower group had significantly longer OS (P < 0.001) and DFS (P=0.06) while patients in the PDK4-lower group had shorter OS (P=0.08) and significantly shorter DFS (P < 0.05), which was also validated by univariate and multivariate Cox regression analyses (Figures S8 and S9).