As for the molecular features, most frequently altered genes in localized DLBCL included PIM1, TET2, KMT2D, BTG2, BTG1, MYD88, ARID1A, HIST1H1E, MPEG1, TNFAIP3, TP53, CREBBP, FAS, GNA13, and TMSB4X, which were also reported to be commonly mutated in DLBCL (27, 28). The gene discussed is TP53; the disease is diffuse large B-cell lymphoma.