Propanoate metabolism-related proteins were significantly increased in ovarian cancers relative to controls (fold change > 1.5), including GSTK1 (fold change = 2.13, p = 4.20E − 5), ACAA1 (fold change = 2.70, p = 1.00E − 2), NUDT19 (fold change = 1.55, p = 6.40E − 3), PECR (fold change = 1.57, p = 4.14E − 4), PEX13 (fold change = 1.61, p = 3.58E − 3), PEX14 (fold change = 1.99, p = 6.51E − 4), IDH2 (fold change = 2.02, p = 2.07E − 3), ABCD3 (fold change = 1.99, p = 6.51E − 4), and PHYH (fold change = 1.94, p = 7.71E − 3). This evidence concerns the gene IDH2 and ovarian cancer.