According to the Online Mendelian Inheritance in Man’s “Gene-Phenotype Relationships,” certain variants of SERPINA1 gene are associated with: (1) Emphysema due to AAT deficiency (# 613490); (2) Emphysema-cirrhosis, due to AAT deficiency (# 613490); and (3) Hemorrhagic diathesis due to antithrombin Pittsburgh (# 613490; https://www.omim.org/entry/107400, accessed 10, 2020). This evidence concerns the gene SERPINA1 and alpha 1-antitrypsin deficiency.