PPARG and cancer: There is increasing evidence indicating that activation of peroxisome proliferator-activated receptor gamma (PPARγ) by its ligands can inhibit the growth of thyroid cancer, likely via multi-mechanisms including stimulation of the anti-tumor immune system, induction of cancer cell differentiation, increase of radioiodine uptake in thyroid cancer cells, cell cycle arrest, and promotion of apoptosis of cancer cells (1–12).